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4C Medical Technologies (Brooklyn Park, MN) is focused on minimally invasive therapies for structural heart disease, specifically mitral valve regurgitation…
Arena Therapeutics (Edina, MN) has evidence that suggests deep brain stimulation applied early in Parkinson’s disease will slow disease progression. If confirmed, each of the 60,000 PD patients diagnosed each year in the U.S. should receive the treatment, representing annual revenue potential of $1.2B (U.S). The company is seeking funding to confirm these findings in a Phase III trial.
Augustine Temperature Management (Eden Prairie, MN) – HotDog electric warming improves outcomes by warming surgical patients. This “next gen” technology is air-free/safer, more effective and more cost effective than the current standard, forced-air warming (FAW). HotDog is uniquely positioned to take advantage of the opportunity resulting from FAW being the target of mass tort litigation for causing hip and knee implant infections.
Brain+ (Copenhagen, Denmark) provides digital cognitive health therapeutics that combine neuro-games and behavioural therapy to recover cognitive injuries and impairments, prevent cognitive decline, and improve mental health.
CereVasc (Boston, MA) is developing the eShunt System, a minimally-invasive, endovascular, cerebrospinal fluid shunt and delivery device intended to treat communicating hydrocephalus including NPH.
Corvida Medical (Coralville, IA) has developed the Halo Closed System Transfer Device, a product designed to prevent clinicians from being exposed to hazardous medications such as those used in chemotherapy.
ENDRA Life Sciences (Nasdaq: NDRA) is a developer of enhanced ultrasound technologies. ENDRA’s next generation Thermo-Acoustic Enhanced UltraSound (“TAEUS”) platform will enable clinicians to visualize human tissue composition, function and temperature in ways previously possible only on CT & MRI – at a fraction of the cost, at the point-of-care. ENDRA’s first clinical application will focus on Non-Alcoholic Fatty Liver Disease, which affects over 1 billion people globally.
EP Technologies (Akron, OH) is developing needleless drug and cosmetic delivery platform. We are experts in tuning cold plasma devices to deliver partners’ formulations into the skin or bloodstream for uniquely safe and efficacious treatments.
FemPulse (Mahtomedi, MN) is developing an elegant and affordable solution for the millions of women afflicted by the symptoms of overactive bladder (OAB). The internally wearable neuromodulation ring delivers small pulses of therapeutic stimulation directly to the nerves that control the bladder to restore function and personal freedom all under the simple and discreet control of a smart phone app.
Health Tech Solutions (Iowa City, IA) is a health-IT company that uses AI and intelligent communication technology to reduce organ discards. Currently, 54% of donated organs go unused in the US every year. HTS is clinically live and facilitates a majority of the organ transplants in Iowa, where the company is headquartered.
Hemovent GmbH (Aachen, Germany) is an emerging medical device company that has developed disruptive technology: the world’s smallest and first self-contained fully portable Extra Corporeal Membrane Oxygenation (ECMO) system that supports or replaces heart and lung function in the event of cardiac and respiratory failure.
ICHOR Vascular Inc. (Minneapolis, MN) is developing a Percutaneous Reperfusion System to treat acute limb ischemia, under-reported embolic / thrombotic events, and organized peripheral clot physicians routinely face. ICHOR’s inaugural technology; Panacea, is a one size fits all system that replicates the parameters of surgical clot removal with reduced surgical and drug complications and eliminates the need for general anesthesia. The technology is easily adoptable by interventionalists and incorporates a health economic element that will make Panacea a first line therapy for physicians.
Impleo Medical (St. Paul, MN) is developing a minimally invasive injection therapy for gastro-esophageal reflux disease, GERD. GERD affects over 60 million people in the U.S. causing heartburn, regurgitation, chest pain, and other symptoms, undermining patients’ sleep, productivity, and overall quality of life. Impleo’s medical device, Aluvra, is a proprietary bulking agent injected in the lower esophagus during an endoscopic procedure.
Isomark’s (Madison, WI) breath technology pre-symptomatically detects severe infections and monitors a patient’s response to treatment. Other applications include macronutrient metabolism feedback for weight management, fitness performance and those receiving supplemental nutrition.
Listen AS (Oslo, Norway) is redefining hearing solutions through disruptive technology. Through the app Mobile Ears, create a customized hearing profile to hear everything clearly and amplify speech.
Mardil Medical’s (Plymouth, MN) VenTouch® Targeted Ventricular Reshaping System is re-defining the mitral disease category by directly addressing the root cause mechanism of functional MR, the diseased and distorted ventricle, not just the healthy but leaky valve.
Metamodix (Plymouth, MN) has developed a drug-free, nonsurgical device therapy designed to reduce weight and eliminate symptoms in those who suffer from Obesity and Type 2 Diabetes.
Microsurgical Innovations (Salt Lake City, UT) is developing a vascular coupling device (VCD), which would replace the hand suturing technique currently used to connect arteries and veins in microvascular and macrovascular end-to-end vascular repair surgeries. Our device works for both arteries and veins and can rapidly connect the two vessel ends together in a watertight seal without leaving any foreign material in the lumen to come in contact with flowing blood.
Nanova (Columbia, MO) is developing dual-functional and non-drug based coronary stents to prevent both restenosis and late thrombosis for safer and more effective treatment of coronary heart disease.
Nascent Surgical’s (Eden Prairie, MN) “miniSquair®” is a highly efficient disposable device that captures 99.0% of smoke and bioaerosols produced in the immediate area of the surgical wound resulting from cauterization of tissue.
NaviSonics (Seattle, WA) – A small, inexpensive neuro-surgical navigation system to quickly and accurately guide placement of ventricular catheters and shunts at the bedside or in the OR.
Oculogica (New York, NY) is using ocular motility and other domains of brain function to detect cranial nerve function. The investigational EyeBOX provides a BOX Score indicative of the presence and severity of brain injury.
Patrona Medical’s (Greenville, SC) new device “Foley Garde” comes in two configurations, wireless and a non-wireless model. The Foley Garde monitors the patient’s urine stream, as urine flows from the patient’s bladder via a Foley catheter the urine saturates a disposable urine filter. The filter is designed to change colors if nitrite and leukocytes are detected in the urine. A patented high-resolution sensor array monitors these color variations and calculates a numeric value a color frequency. The Foley Garde transmits alerts and messages to the healthcare staff over a cellular, wireless or directly to the device display screen.
Peytant Solutions (Plymouth, MN) is transforming the treatment of luminal diseases through regenerative medicine.
Priya, developed by Prima-Temp (Boulder, CO), is a revolutionary personal fertility sensor that passively and continuously tracks a woman’s core body temperature, detecting the subtle changes that occur before ovulation, then sends an alert to her phone when she’s most fertile.
Pristine Surgical (Bedford, NH) has developed an integrated surgical imaging system for rigid endoscopy (arthroscopy and laparoscopy) which provides a crystal-clear HD view in a clean, low cost, hassle free single-use device.
Standard Bariatrics (Cincinnati, OH) is a med device-focused company in Laparoscopic Sleeve Gastrectomy market with compelling clinic data and the ability to lower supply cost with our STANDARD Sleeve Gastrectomy family of products including a proprietary endoscopic stapler. Our first product, STANDARD CLAMP (TM), is 510(k) approved and on the US Market.
TheoremDx (Edina, MN) is an in vitro diagnostics company transforming rapid molecular testing for infectious diseases and antimicrobial resistance at the point of care. The company’s revolutionary digital electronic testing system gives highly sensitive and reliable molecular bacterial identification and bacterial resistance status, in minutes, without the need for chemical reagents or standard culture techniques.
TherVoyant (Madison, WI) creates comprehensive software and hardware solutions to enable image-guided medical procedures inside of a standard clinical MRI scanner. Our goal is to make Real-Time MRI fast and simple enough so that it is as useful as fluoroscopy, but with the improved resolution of MRI which is needed for high-value interventional surgeries.
Tivic Health Systems (Menlo Park, CA) is bringing to market a new treatment for sinus pain and pressure. SYNUS pain relief, based on a novel microcurrent therapy, offers unprecedented relief without pills, sprays, or nasal flush.
UroCure (Edina, MN) is focused on re-commercializing two market-leading slings from IP acquired from AMS/Endo Women’s Health for the treatment of female incontinence.
Urotronic, Inc. (Minneapolis, MN) was founded in December 2014 to research, develop and commercialize a proprietary drug coated balloon that will transform the urinary tract stricture and benign prostate hyperplasia (BPH) market through better patient outcomes and in-office ease of use uniquely positioned for today’s healthcare environment.
Woven Orthopedic Technologies (Manchester, CT) is a medical device business that designs and develops orthopedic technologies to treat the rapidly aging global population affected by orthopedic conditions. Our premiere technology addresses the #1 problem with the #1 technology used in orthopedics today by enhancing screw fixation in patients who receive treatment for fractures.
Zift Medical (Minnetrista, MN) is developing an implant for minimally invasive aesthetic procedures such as a brow-lift, and is currently enrolling in a US FIH study.